PEGylation with Precision
Polyethylene glycol (PEG) is a water-soluble polymer with a wide range of applications. PEGylation, the process of attaching PEG to proteins and drugs, is widely used in the pharmaceutical industry to impart hydrophilicity and ‘stealth’ properties to therapeutics. Exactmer supplies exact-PEGs with unique purity.
Nanostar Sieving™ technology allows each monomer to be added one at a time to the growing polymer, resulting in ‘monodisperse’ (i.e., unimolecular) PEGs with unparalleled precision and control over the molecular weight (MW).
Functional End-Group Chemistries
We are experts in PEG chemistry, and provide a range of end-group functionalities on our unimolecular PEGs. We also provide consultations to create bespoke molecules, tailored for our clients’ needs. Exactmer’s unimolecular PEGs are made with unmatched precision, eliminating the need for purification by chromatography, and maintaining unrivalled uniformity even at high-MW >2k Da.
The advantages of Exactmer PEGs
Exactmer produce PEGs that are a cut above the rest. Uniquely monodisperse at high molecular weights, Exactmer’s PEGs can alleviate the analysis of new therapeutics, streamlining the drug development process, ultimately accelerating the journey from research to the clinic.
High Molecular Weights
Nanostar Sieving™ allows for unprecedented control over polymer synthesis, even at high Molecular Weights (MWs). Exactmer specialises in the synthesis and supply of unimolecular (monodisperse) PEGs with MW > 2 kDa.
Simplified Analysis
Using unimolecular (monodisperse) PEGs results in less complicated analysis, streamlining the development of your PEGylated therapeutics from discovery through to the clinic, saving you time and money.
Discrete Activities
Exact PEGs allow for better predictability and consistency of action in biomedicine. Using disperse polymers could lead to diverse activity in vivo.
The journey starts here
We are committed to support the delivery of first-class advanced pharmaceuticals. Let’s explore how we can work together.
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