Precision-engineered membranes for exact polymer manufacturing
Exactmer pairs proprietary organic solvent-stable membranes with Nanostar Sieving®, our fully liquid phase synthesis platform, to give pharmaceutical manufacturers a lower-cost, more scalable and more sustainable route to oligonucleotide therapeutics.
- Reduced manufacturing costs
- Unlocked scalability
- Improved sustainability
Advanced Separation Technologies
Years of expertise in organic solvent nanofiltration (OSN) membranes underpin our membrane lines and Nanostar Sieving®, our flagship fully liquid phase synthesis platform.
OSN Membrane Platform
Exact‑10, Exact‑01™ and Exact‑20™ cover upstream synthesis, solvent recovery and downstream purification, available as flat sheets or spiral wound modules.
View membrane specifications →Nanostar Sieving®
An automated, fully liquid phase synthesis process that reduces solvent consumption, leveraging size and shape via OSN to isolate highly pure, specific molecular components.
See how it works →OSN membranes across the full process
From synthesis through to final purification, Exact‑10, Exact‑01™ and Exact‑20™ are tuned to a different stage of the same liquid phase process.
Upstream Synthesis
Chemistry-agnostic separation for the Nanostar Sieving® iterative synthesis process.
Solvent Recovery
Recycles process solvent, reducing consumption and manufacturing cost.
Downstream Purification
TFF-style downstream purification of the final polymer product.
OSN membranes spanning the full process
Our advanced membrane capabilities enable the production of membranes with unparalleled stability in organic solvents, and high permeance, selectivity and durability. From our Advanced Membrane Manufacturing Suite in Dagenham, we produce a range of membranes tailored to the needs of specific applications.
Exact-10â„¢
The membrane behind Nanostar Sieving® for exact polymer synthesis, purifying the growing chain at every iteration.
View specificationsExact-01â„¢
In-process solvent recycling, reducing virgin solvent consumption without energy-intensive distillation.
View specificationsExact-20â„¢
Tangential Flow Filtration membranes optimised for concentration, solvent exchange and by-product removal, with limited fouling and high yield.
View specificationsBuilt for a variety of advanced polymer therapeutics
Exactmer creates technologies to provide customers with high quality, scalable and efficient synthesis processes. We work with customers to understand their specific needs and develop solutions that meet their exact specifications.
Oligonucleotide Synthesis
Nanostar Sieving® supports ASO, siRNA, miRNA and saRNA chemistries, holding the record for the longest oligo made exclusively in liquid phase.
Learn more →Other Advanced Polymer Therapeutics
Exactmer's selective nano-separation extends beyond oligonucleotides to peptides, ADC linkers, and unimolecular PEGs.
Learn more →A team built around the platform
Advanced Membrane Manufacturing
Highly effective membranes, stable in organic solvents, with high selectivity and permeance.
Analytical Excellence
Accurate, reliable and timely analytical data to support product development, quality control and regulatory compliance.
Technology Transfer & Supply Agreement
A Nanostar Sieving® synthesizer at your site, including membrane supply and technology licensing.
Highly Qualified Team
Deep expertise in polymer synthesis and development, across a growing team of specialist staff.
Start with a technical batch
We prioritise collaboration with our customers, offering small-scale technical batches to demonstrate the capabilities of our technology against your polymer specification. Ready to integrate Nanostar Sieving® into your in-house process? Talk to our team about a technology transfer.
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