Precision-engineered membranes for advanced polymer therapeutic manufacturing
Exactmer pairs proprietary organic solvent-stable membranes with Nanostar SievingĀ®, our fully liquid phase synthesis platform, to give pharmaceutical manufacturers a lower-cost, more scalable and more sustainable route to oligonucleotide therapeutics.
Solid phase synthesis limits scalability and sustainability, restricting who oligonucleotide therapeutics can reach.
Exactmer's membrane platform is built to remove that bottleneck, so life-saving oligo drugs can reach more of the patients who need them.
Nanostar SievingĀ®
An automated, fully liquid phase synthesis process that reduces solvent consumption, leveraging size and shape via OSN to isolate highly pure, specific molecular components.
Reduced manufacturing costs
Unlocked scalability
Improved sustainability
Process-wide membrane applications
Separation happens at every stage of oligonucleotide manufacturing. Exactmer's OSN membranes perform those separations in organic solvents, replacing more resource intensive conventional steps.
Exact-10ā¢
The synthesis membrane facilitating Nanostar SievingĀ® for liquid phase synthesis, purifying the growing chain at every iteration.
Exact-01ā¢
In-process solvent recycling, reducing virgin solvent consumption without energy-intensive distillation.
Exact-20ā¢
TFF membranes optimised for concentration, solvent exchange and by-product removal, with high purities and high yields.
Available as flat sheets or spiral wound modules.
Built for a variety of advanced polymer therapeutics
Exactmer creates technologies to provide customers with high quality, scalable and efficient synthesis processes. We work with customers to understand their specific needs and develop solutions that meet their exact specifications.
Oligonucleotide Synthesis
Nanostar SievingĀ® supports oligonucleotide (ASO, siRNA, miRNA and saRNA) synthesis chemistries for scalable manufacturing fully in liquid phase.
Learn more ā
Other Advanced Polymer Therapeutics
Exactmer's selective nano-separation extends beyond oligonucleotides to peptides, ADC linkers and unimolecular PEGs, now in research and development.
Learn more āStart with a technical batch
We prioritise collaboration with our customers, offering small-scale technical batches to demonstrate the capabilities of our technology against your polymer specification. Ready to integrate Nanostar SievingĀ® into your in-house process? Talk to our team about a technology transfer.
Explore our services ā
